1.Open PowerShell ISE
2.Create and open your profile with:
New-Item -Path $Profile -ItemType file -Force
notepad $profile
3.Notepad will open with an empty file. Enter the following command:
PowerCli 6.0:
& 'C:\Program Files (x86)\VMware\Infrastructure\vSphere PowerCLI\Scripts\Initialize-PowerCLIEnvironment.ps1'
PowerCli 6.5:
& 'C:\Program Files (x86)\VMware\Infrastructure\PowerCLI\Scripts\Initialize-PowerCLIEnvironment.ps1'
4.Restart PowerShell ISE
https://www.virten.net/2016/07/how-to-properly-initialize-powercli-6-x-in-powershell-ise/