import sounddevice as sd
from scipy.io.wavfile import write

fs = 16000 # Sample rate
seconds = 5 # Duration of recording

myrecording = sd.rec(int(seconds * fs), samplerate=fs, channels=1)
sd.wait() # Wait until recording is finished
write('output.wav', fs, myrecording) # Save as WAV file

simpleaudio

portaudio

sounddevice