Grid

<Grid Background="LightBlue">

        <Grid.RowDefinitions>

            <RowDefinition Height="auto" />

            <RowDefinition />

            <RowDefinition />

            <RowDefinition />

        </Grid.RowDefinitions>

       

        <Grid.ColumnDefinitions>

            <ColumnDefinition Width="auto" />

            <ColumnDefinition />

        </Grid.ColumnDefinitions>

       

        <Label Grid.Row="0" Grid.Column="0" Background="Blue" Foreground="White"

               HorizontalContentAlignment="Center" Grid.ColumnSpan="2">Start Page</Label>

       

        <GroupBox Grid.Row="1" Grid.Column="0" Background="White"

                  Header="rencent Projects">_</GroupBox>

       

        <GroupBox Grid.Row="2" Grid.Column="0" Background="White"

                  Header="Getting Started">_</GroupBox>

       

        <GroupBox Grid.Row="3" Grid.Column="0" Background="White"

                  Header="Headlines">_ </GroupBox>

       

        <GroupBox Grid.Row="1"  Grid.Column="1" Background="White"

                  Header="Online Articles"  Grid.RowSpan="3">

            <ListBox>

                <ListBoxItem>Article #1</ListBoxItem>

                <ListBoxItem>Article #2</ListBoxItem>

                <ListBoxItem>Article #3</ListBoxItem>

                <ListBoxItem>Article #4</ListBoxItem>

            </ListBox>

        </GroupBox>

</Grid>