1.  打开文件夹: C:\Program Files(X86)\Vmware\Infrastructure\Virtual Infrastructure Client\Launcher
2.  编辑文件 VpxClient.exe.config 增加如下内容(红色显示):
<?xml version="1.0" encoding="utf-8"?>
<configuration>
  <system.net>
        <connectionManagement>
            <clear/>
            <add address="*" maxconnection="8" />
        </connectionManagement>
    </system.net>
  <appSettings>
    <add key = "protocolports" value = "https:443"/>
  </appSettings>
<runtime>
 <developmentMode developerInstallation="true"/>
</runtime>
</configuration>
3. 
创建一个文件夹,放dotnet2.0的 System.dll 放到新建的文件夹中。
4. 编辑系统的环境变量,新增一个叫DEVPATH环境变量,值就是你放dotnet2.0的System.dll的目录,比如我的:
     C:\Program Files(x86)\VMware\Infrastructure\Virtual Infrastructure Client\Launcher\Lib
现在,vSphere client 应该可以工作了。

But the Host Update Utility still won't work, so there's just one additional steps to get that working:
5.  Copy VpxClient.exe.config file (from above) to the following location, re-naming it VIUApp.exe.config:
     C:\Program Files (x86)\VMware\Infrastructure\VIUpdate 4.0\
注意一下,这个里面说到的System.dll文件可以在XP等之类的装了.net 2.0的机器上复制到,具体位置位于
%SystemRoot%\Microsoft.NET\Framework\v2.0.50727\System.dll,Win7自带的就是.net 3.5了。