$strPath="d:\temp\newuser.xls"

$objexcel=new-object -comobject excel.application

$workbook=$objexcel.workbooks.open($strpath)

$worksheet=$workbook.sheets.item("sheet1")

$worksheet.cells.item(1,1).value2="daniel09999"


$workbook.save()

$objexcel.quit()



参考链接：

http://www.cnblogs.com/fuhj02/archive/2010/12/23/1914313.html